Dr. Diana Rangaves, PharmD

Reus Research NAD: Unlocking the Secrets to Longevity and Health

Updated on November 24, 2025

In the heart of Catalonia, the city of Reus is quietly becoming a center of cutting-edge health research. Among its notable scientific efforts is the study of NAD (Nicotinamide Adenine Dinucleotide). This is a molecule increasingly recognized for its potential to extend lifespan, improve energy metabolism, and support healthy aging. Longevity, maybe, quality of life? Unknown.

In this article, we explore what recent Reus research on NAD reveals about the molecule’s impact on human health and longevity and how these findings may influence the future of medicine.

What Is NAD and Why Is It Important?

This coenzyme is present in every living cell and plays a key role in energy conversion, DNA repair, and cellular signaling. As the body ages, levels of this molecule begin to drop, which can lead to fatigue, metabolic imbalance, and visible signs of aging.

Supporting healthy levels of this cellular compound has been associated with:

  • Better mitochondrial performance
  • Improved cognitive and cardiovascular function
  • Lower inflammatory response
  • Stronger internal repair processes

Why Reus Is Gaining Attention in NAD Research

Reus, located in the province of Tarragona, is home to research institutions such as the Institut d’Investigació Sanitària Pere Virgili (IISPV) and the Universitat Rovira i Virgili (URV). These institutions are involved in metabolic and nutritional research, including the effects of NAD precursors like NMN (Nicotinamide Mononucleotide) and NR (Nicotinamide Riboside) on aging and chronic diseases.

Key areas of interest from Reus-based research teams include:

  • The role of NAD in age-related metabolic diseases
  • How does it influence the cellular stress response
  • Links between declining levels and neurodegenerative conditions

What Does Reus-Based Research Say About Longevity?

Recent projects from researchers in Reus have explored how boosting this coenzyme could delay the onset of age-related conditions. One study, supported in part by IISPV and local clinical collaborators, looked at how its metabolism changes with aging and how it might be targeted through diet and supplementation.

Notable findings:

  • Declining levels of this cellular compound are common in older adults with metabolic disorders like type 2 diabetes and obesity
  • Precursors such as NR have shown potential to reverse mitochondrial decline
  • Regular intake of vitamin B3 derivatives may enhance sirtuin activity—a family of proteins linked to increased lifespan and better cellular function

These findings align with global research suggesting that maintaining healthy levels of this molecule could be key to healthy aging. For additional reading, visit this overview from the NIH on NAD+ metabolism.

Best NAD Supplements for Healthy Aging

Research from Reus and other global institutions has increased interest in supplements that safely support cellular energy and repair. These options are widely used in the U.S. and easily available on Amazon.

1. Liposomal NMN

A liposomal formula can improve absorption and help raise NAD levels more efficiently.
A liposomal NMN supplement is popular for energy, exercise recovery, and overall cellular support.

2. Standard NMN Capsules

A classic option that many longevity researchers prefer.
An NMN supplement helps support mitochondrial energy, DNA repair pathways, and sirtuin activation.

3. Nicotinamide Riboside (NR)

Known for excellent bioavailability and strong clinical data.
A high-quality NR supplement may help support healthy metabolism, cognitive performance, and long-term NAD maintenance.

4. Liposomal NAD+ Drops

These deliver NAD+ directly in a liquid form that absorbs quickly.
People often useliposomal NAD+ supplements for fast energy support and mental clarity.

5. Resveratrol or Pterostilbene

Antioxidants that work alongside NMN/NR to support sirtuins and reduce oxidative stress.
A Resveratrol supplement is commonly paired with NAD boosters as part of a combined approach.

6. MitoQ (Mitochondrial Antioxidant)

Targets mitochondria directly to reduce oxidative damage.
A MitoQ antioxidant supplement supports cellular resilience, exercise recovery, and energy production.

7. NAD IV-Style Oral Booster Formulas

Some blends combine NMN, NR, CoQ10, TMG, and antioxidants.
A complete NAD booster formula can help people who prefer an all-in-one option.

Clinical Applications Under Review in Reus

While many studies are still in early clinical or preclinical phases, researchers in Reus are exploring several promising applications linked to this metabolic coenzyme:

  • Cellular coenzyme IV infusions for chronic fatigue syndrome
  • Neuroprotective potential in Alzheimer’s disease research
  • Enhanced metabolic flexibility in older adults

Teams are also evaluating how dietary patterns and fasting protocols may stimulate the body’s natural production of this compound, positioning lifestyle medicine as a practical companion to supplementation.

How This Cellular Molecule Influences Aging and Health

Here’s how maintaining optimal levels of this molecule may contribute to longer, healthier lives:

Energy metabolism

It helps mitochondria convert food into energy. Higher levels of this compound can improve stamina, reduce fatigue, and support muscle health.

DNA repair

This cellular molecule activates repair enzymes like PARP1 and sirtuins that fix damaged DNA and extend cellular life.

Inflammation control

Chronic low-grade inflammation contributes to aging. It helps regulate immune responses and reduces inflammation at the cellular level.

Brain function

It may enhance cognitive performance and protect neurons from age-related decline.

Future of NAD-Based Therapies in Reus

Research centers in Reus are now part of Europe-wide clinical trials focused on testing the long-term safety and effectiveness of these cellular energy therapies. These studies are exploring how such supplements could work alongside standard treatments for:

  • Cardiovascular disease
  • Metabolic syndrome
  • Neurodegenerative disorders
  • Immune decline in older adults

If these trials continue to show positive outcomes, Reus has the potential to position itself as a key European hub for advanced coenzyme-based research and clinical applications.

Conclusion:

The growing interest in Reus’ longevity research signals a major shift in how modern medicine views aging and prevention. By exploring how this cellular coenzyme influences energy balance, metabolic resilience, and repair mechanisms, researchers from the region are adding valuable insight to global health discussions. More information and studies are needed.

Yet, as more trials and nutritional protocols come forward, this molecule could become a core element of future preventive strategies, with Reus establishing itself as one of Europe’s forward-thinking health innovation hubs.

FAQs

What is Reus’s research on NAD about?

Using basic science and clinical trials, Reus-based scientists study how it influences aging, energy metabolism, and chronic diseases.

Which institutions are involved in NAD research in Reus?

The Institut d’Investigació Sanitària Pere Virgili (IISPV) and Universitat Rovira i Virgili (URV) are key players.

Is Supplementing This Coenzyme Safe?

Early findings show that precursors like NMN and NR appear safe when used in controlled doses, but long-term human studies are still underway.

How can I naturally Support Coenzyme Production?

Exercise, intermittent fasting, and foods rich in vitamin B3—like salmon, mushrooms, and avocados—can help the body maintain healthy coenzyme levels.

Sirtuins and their connection to this Coenzyme?

Sirtuins are a group of proteins that depend on this cellular coenzyme to activate. They play an important role in DNA repair, metabolic balance, and are often studied for their link to healthy aging and longevity.

Are there any clinical trials in Spain?

Yes, Spain especially research hubs like Reus is actively involved in several ongoing trials focused on cellular coenzyme therapy and its potential benefits for age-related conditions.

Are there longevity clinics?

As more wellness and longevity clinics begin offering NAD+ IV and injection therapies, proper handling of medical waste is becoming increasingly important. Used needles and syringes must be collected and disposed of safely to protect both staff and patients. Clinics in Tennessee often partner with trusted providers offering sharps disposal Nashville services to stay compliant with health regulations and maintain a clean, professional environment.

Can NAD help prevent aging?

While it can’t stop aging, NAD may help slow the process by supporting better cellular health, energy production, and DNA repair.

How is Reus different from other research hubs?

Reus offers a unique combination of clinical excellence, nutritional science, and integrative research, making it a promising center for NAD longevity research.

What’s Next?

Curious about how cellular energy molecules influence recovery, DNA repair, and overall vitality?
Explore our detailed guide on energy metabolism and cellular repair pathways to understand how these processes support healthy aging.

If you’re interested in going deeper into longevity research, take a look at the PubMed index on sirtuins and metabolic pathways for peer-reviewed scientific data.

Resources