Written by: Ahsan Riaz
Reviewed by: Dr. Diana Rangaves, PharmD, RPh — Pharmacist, Medical Writer, and Author

Bromphen PSE DM. Ever had one of those stubborn colds that just won’t go away? The kind that leaves you with a stuffy nose, constant sneezing, and a dry cough that keeps you up at night? That’s where Bromphen PSE DM often steps in.

It’s a combination cold and cough medicine that helps you breathe easier, stop coughing, and get some proper rest. Let’s break it down so you know exactly what you’re taking — and how to use it safely.

What Is Bromphen PSE DM?

Bromphen PSE DM is an acronym for Dextromethorphan, Pseudoephedrine, and Brompheniramine. Every one of these components has a distinct function:

• Brompheniramine: an antihistamine that relieves watery eyes, runny nose, and sneezing.
• Dextromethorphan is a cough suppressant that reduces the urge to cough, and pseudoephedrine is a decongestant that constricts swollen nasal passages to facilitate breathing.

They work together to address several cold, allergy, and upper respiratory infection symptoms.

The most widely used formula is Bromphen-PSE-DM 2-30-10 mg per 5mL syrup, which means that each teaspoon has 10 mg of dextromethorphan, 30 mg of pseudoephedrine, and 2 mg of brompheniramine.

You can also go to WebMD’s official page on Bromphen PSE DM to learn more about its composition.

Available Forms and Strengths

Although liquid syrup is the most common form, there are other forms as well. Depending on your age and symptoms, your doctor may prescribe it as an extended-release medication or as tablets.

The following are typical versions that you may find on labels:

• Brompheniramine-Pseudoephedrine-Dextromethorphan 2-30-10 mg/5mL syrup: the most widely used for both children and adults.
• Bromphen-PSE-DM-Acetaminophen: this medication also contains a fever reducer and pain reliever.
• Bromfed DM: a branded product that contains the same essential components.
• Bromphen PSE DM tablets or capsules are less common and are typically only prescribed to adults.

For children and those who require flexible dosing, the syrup form is recommended. For adults who want relief that lasts longer, tablets are more convenient.

No matter the form, always read the label carefully — even small differences in ingredients or strength can change how it affects you.

What Symptoms Does It Help With?

You can use Bromphen PSE DM to manage:

• Sneezing and itchy eyes
• Runny or congested nose
• Postnasal drip
• Sinus pressure
• Cough from throat irritation or cold

It doesn’t cure the infection, but it can make you feel human again while your body fights it off.

Bromphen PSE DM for Kids

Is it safe for kids? is a question that parents frequently ask.

Yes, but only under very strict dosage instructions. Children are frequently prescribed the syrup to relieve congestion and coughing, but it must be used with caution.

Generally speaking, children under the age of six shouldn’t take it unless their doctor specifically prescribes it. Serious side effects like agitation, a fast heartbeat, or drowsiness can result from overdosing or administering too much too soon.

Never use a kitchen spoon; always use the syringe or measuring cup that is provided. Additionally, avoid combining it with other over-the-counter cold remedies.

Stop the medication and give your doctor a call if your child experiences unusually high levels of sleepiness, dizziness, or restlessness after taking it.

Bromphen PSE DM Dosage Chart

Dosing depends on age and sometimes on weight. Here’s a general reference chart based on common 2-30-10 mg/5mL formulations:

Age Group	Dosage	Frequency
Adults & children 12+	10 mL (2 tsp)	Every 4 hours as needed
Children 6–12 years	5 mL (1 tsp)	Every 4 hours as needed
Children under 6	Only if prescribed	Doctor’s supervision required

Do not exceed 6 doses in 24 hours.
If you miss a dose, take it when you remember — unless it’s almost time for the next one. Never double up.

Possible Side Effects

Like most cold medications, it can cause some side effects. They’re usually mild but worth keeping an eye on.

Common ones include:

• Dry mouth or nose
• Drowsiness or dizziness
• Headache
• Upset stomach

Less common but more serious reactions may include:

• Fast or irregular heartbeat
• Tremors
• Confusion or hallucinations
• Seizures (rare but possible if overdosed)

If you experience chest pain, difficulty breathing, or severe restlessness — stop using it and get medical help right away.

Precautions and Warnings

Before taking it, make sure your doctor knows if you have:

• High blood pressure
• Diabetes
• Thyroid disorders
• Heart disease
• Glaucoma
• Prostate problems

This medicine can worsen those conditions or interact with other drugs you might be using.

Also, avoid taking it if you’ve used MAO inhibitors (a type of antidepressant) within the last 14 days — that mix can be dangerous.

Pregnancy and Breastfeeding

If you’re pregnant or breastfeeding, use Bromphen PSE DM only if your doctor says it’s safe.
A small amount of the medicine may pass into breast milk, so it’s best to talk to a healthcare provider before taking it.

Is Bromphen PSE DM a Controlled Substance?

No, it is not classified as a controlled substance.

This means that, unlike drugs or addictive cough syrups that contain codeine, it is not strictly regulated by the federal government.

However, you should not misuse it. Overdosing, particularly on the dextromethorphan component, can result in harmful side effects or abuse.

Because of its sedative or mild euphoric effects, some people attempt to use it recreationally, which is dangerous and could be harmful. Always heed medical advice.

Interactions You Should Know About

It can interact with:

• Antidepressants (like MAOIs or SSRIs)
• Blood pressure medications
• Other cough or cold medicines
• Alcohol or sedatives

Mixing these can amplify drowsiness or raise blood pressure. Always read labels before combining drugs.

What If You Take Too Much Bromphen PSE DM?

Taking too much can cause severe drowsiness, rapid heartbeat, high blood pressure, confusion, or seizures.
If this happens, get emergency medical help immediately or call your local poison control center.
Never try to make yourself vomit unless told by a professional.

Tips for Safe Use

A few small things make a big difference:

• Drink plenty of water to loosen mucus
• Avoid alcohol or sleep aids
• Take it during the day if you don’t feel sleepy — or at night if it makes you drowsy
• Store the bottle tightly closed and away from kids

Storage Instructions

Keep Bromphen PSE DM at room temperature, away from direct sunlight, heat, and moisture.
Never freeze the syrup, and make sure the cap is closed tightly after each use.

Key Takeaways

• Bromphen PSE DM combines three ingredients — brompheniramine, pseudoephedrine, and dextromethorphan — to relieve cold and cough symptoms.
• The 2-30-10 mg/5mL syrup is the most common form used for both adults and kids (under medical supervision).
• It’s available in other combinations like Bromphen PSE DM with acetaminophen or Bromfed DM.
• Helps with congestion, cough, runny nose, and sinus pressure.
• Not a controlled substance, but should be taken responsibly.
• Avoid double dosing or mixing it with similar cold medicines.
• Always check with your doctor if you have high blood pressure, heart problems, or diabetes.

References

1. WebMD: Bromphen PSE DM Oral Details
2. Kaiser Permanente Health Encyclopedia – Brompheniramine Pseudoephedrine DM

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer