Finding a loose white pill in a pocket, medicine drawer, or unlabeled container creates immediate uncertainty. The imprint may be visible, but the medicine and strength are not certain. A white, round pill with R over P on one side and 10 on the other is commonly identified as oxycodone hydrochloride 10 mg, an immediate-release prescription opioid used to manage severe pain.
Pharmacists do not identify a pill by color or a partial marking alone. Both sides, the complete imprint, shape, size, and original container matter because similar RP 10 markings appear on different medicines, and counterfeit pills can copy a genuine tablet’s appearance. If the pill did not come from a licensed pharmacy in its labeled container, do not take it. Ask a pharmacist to confirm the identification.
Emergency: If someone cannot be awakened or has slow or stopped breathing, give naloxone if available and call 911. For a possible accidental ingestion without emergency symptoms, call Poison Control at 1-800-222-1222.
RP 10 Pill Identification
| Feature | Description |
|---|---|
| Imprint | R over P on one side; 10 on the other |
| Color | White to off-white |
| Shape | Round and raised on both sides |
| Size | About 7 mm |
| Active ingredient | Oxycodone hydrochloride |
| Strength | 10 mg |
| Release type | Immediate-release |
| Drug class | Opioid pain medicine |
| Controlled status | Schedule II prescription drug |
| Contains acetaminophen | No |
These details match the oxycodone hydrochloride 10 mg tablet listed in current U.S. pill and drug-label databases.
What Is the RP 10 Pill
The standard white RP 10 pill contains 10 mg of oxycodone hydrochloride. Oxycodone is a strong opioid medicine. It changes how your brain and nervous system respond to pain.
The RP 10 tablet is an immediate-release product. This means the medicine is released without the special extended-release system used in long-acting tablets.
Oxycodone is a Schedule II controlled substance in the United States. It has accepted medical uses, but it can also cause misuse, addiction, physical dependence, overdose, and death. It should only be taken by the person whose name appears on the prescription.
The original product associated with this imprint is marketed by Rhodes Pharmaceuticals and manufactured by Purdue Pharma L.P. Current databases may also show pharmacy repackagers or relabelers under different company names.
What Does an RP 10 Pill Look Like
A standard oxycodone RP 10 tablet has these features:
- White or off-white color
- Round shape
- About 7 mm wide
- The letter R above a score line and P below it
- The number 10 on the opposite side
Check both sides of a pill when reading an imprint. Spaces, lines, numbers, and extra letters matter. RP 10, RP 10 325, and RP 10 300 do not identify the same medicine.
A score line does not automatically mean you should split a tablet. Only split medication when your prescriber or pharmacist has told you to do so.
How to Check a Pill Imprint Safely
Use the following details together when trying to identify a pill:
- Read the complete imprint on both sides.
- Check the pill’s color and shape.
- Look for a score line, logo, or extra number.
- Compare its size with a ruler if possible.
- Check the prescription bottle and pharmacy label.
- Ask a pharmacist if any detail is unclear.
Do not identify a medicine by color alone. Lighting, surface wear, dirt, and damage can change how a pill looks. An online pill identifier can provide a possible match, but it cannot confirm what is inside an unknown pill.
Pills That May Be Confused With RP 10
Several medicines have imprints that include RP and 10. The complete imprint makes the difference.
| Full imprint and appearance | Possible identification |
|---|---|
| R over P / 10, white round tablet | Oxycodone hydrochloride 10 mg |
| RP / 10 325, white round tablet | Oxycodone 10 mg and acetaminophen 325 mg |
| Logo followed by RP 10, white and blue capsule | Ramipril 10 mg |
| RP 10 mg, pink capsule | Lisdexamfetamine 10 mg |
| RP 10 300, white capsule-shaped tablet | Hydrocodone 10 mg and acetaminophen 300 mg, previously listed product |
These products contain different medicines and are used for different conditions. Never take a pill based only on a partial imprint or a photo.
RP 10 Versus RP 10 325
The RP 10 pill and RP 10 325 pill are easy to confuse, but they do not contain the same ingredients.
| Feature | RP 10 | RP 10 325 |
|---|---|---|
| Oxycodone | 10 mg | 10 mg |
| Acetaminophen | None | 325 mg |
| Main imprint | R/P and 10 | RP and 10 325 |
| Typical shape | Round | Round |
| Approximate size | 7 mm | 10 mm |
| Medicine type | Oxycodone only | Oxycodone-acetaminophen combination |
The number 325 means the combination pill contains 325 mg of acetaminophen. This extra ingredient matters because acetaminophen is also found in many pain, cold, and flu products.
Taking too much acetaminophen can cause severe liver damage. Check every medicine label and ask a pharmacist before combining products that contain acetaminophen or APAP.
As of October 2026, Drugs.com lists the Rhodes RP 10 325 product under “Previously listed products.” A loose tablet still needs source verification because counterfeit pills can copy genuine markings.
Is RP 10 the Same as OxyContin or Percocet
No. These names are related to oxycodone, but they do not describe the same product.
| Product | Active ingredients | Release type | Key difference |
|---|---|---|---|
| RP 10 | Oxycodone 10 mg | Immediate-release | Contains oxycodone only |
| OxyContin 10 mg | Oxycodone 10 mg | Extended-release | Designed to release medicine over a longer period |
| Percocet | Oxycodone and acetaminophen | Immediate-release | Contains two active ingredients |
| RP 10 325 | Oxycodone 10 mg and acetaminophen 325 mg | Immediate-release | Generic combination product |
A 10 mg OxyContin tablet is usually white and round, with OP on one side and 10 on the other. It is not identified by the R/P imprint.
People sometimes call any oxycodone-acetaminophen pill Percocet. Strictly speaking, Percocet is a brand name. An RP 10 325 tablet is a generic oxycodone-acetaminophen product, not the branded Percocet tablet.
What Is the RP 10 Pill Used For
Oxycodone is prescribed for pain severe enough to require an opioid when other treatments are not effective, cannot be tolerated, or are not expected to provide enough relief.
A clinician should choose the dose based on the person’s pain, health, previous opioid use, and response to treatment. Do not use another person’s dose or change how often you take the medicine without medical advice.
The RP 10 pill does not treat the cause of pain. It reduces how strongly the body feels and responds to pain.
How Long Does RP 10 Last
RP 10 is an immediate-release oxycodone tablet, but there is no single duration that applies to everyone. Immediate-release oxycodone is generally prescribed every 4 to 6 hours as needed for pain, though you should take another dose only at the time written on your prescription. Its effects may vary with age, health, previous opioid use, and other medicines.
Studies in the current label report a half-life of about 3.5 to 4 hours for immediate-release oxycodone tablets. Half-life means the time needed for the drug level in the blood to fall by half. It does not tell you when it is safe to take another tablet. Follow only the schedule written on your prescription.
Common RP 10 Side Effects
Common oxycodone side effects include:
- Constipation
- Nausea
- Vomiting
- Dizziness
- Sleepiness
- Headache
- Itching
- Trouble sleeping
- Weakness or low energy
Do not drive or use machinery until you know how oxycodone affects you. It may slow your thinking, movement, and reaction time.
Tell your prescriber if a side effect is severe, does not improve, or makes it hard to take the medicine safely.
Serious Side Effects
Oxycodone can slow breathing, especially when treatment starts, the dose increases, or it is mixed with other substances that cause sleepiness.
Get urgent medical help for:
- Slow, shallow, or difficult breathing
- Long pauses between breaths
- Extreme sleepiness
- Trouble waking up
- Fainting or severe weakness
- Swelling of the face, lips, tongue, or throat
- A severe allergic reaction
- Confusion with fever, sweating, shaking, or stiff muscles
Serotonin syndrome is a rare but serious reaction that may occur when oxycodone is combined with certain medicines that affect serotonin.
Alcohol and Drug Interactions
Do not drink alcohol or use prescription or over-the-counter medicines that contain alcohol while taking oxycodone. The combination can cause severe breathing problems, overdose, and death.
The same risk may increase when oxycodone is taken with:
- Benzodiazepines, such as alprazolam or diazepam
- Sleeping pills
- Other opioids
- Muscle relaxants
- Sedating anxiety medicines
- Some seizure medicines
- Some antidepressants
- Street drugs
- Any medicine that causes strong drowsiness
Certain medicines can also change the amount of oxycodone in your blood. Examples include some antibiotics, antifungal medicines, HIV medicines, and seizure medicines. Give your prescriber and pharmacist a complete list of your prescriptions, over-the-counter medicines, vitamins, and supplements.
Who Should Speak With a Clinician Before Taking Oxycodone
Tell your clinician about all health conditions before using oxycodone. This is especially important if you have:
- A known allergy to oxycodone or any ingredient in the tablet
- Asthma, COPD, sleep apnea, or another breathing problem
- A head injury or seizure disorder
- Low blood pressure
- A blocked intestine or other digestive condition
- Liver or kidney disease
- Problems with the pancreas or gallbladder
- A history of alcohol or drug misuse
- Depression or another mental health condition
- Pregnancy or plans to become pregnant
- Breastfeeding plans
Oxycodone should not be used in people with serious breathing depression, certain cases of severe asthma, or a known or suspected intestinal blockage.
Using oxycodone for an extended period during pregnancy may cause life-threatening opioid withdrawal in a newborn. Oxycodone can also pass into breast milk. A breastfed baby should be checked for unusual sleepiness, breathing trouble, or limpness.
Dependence Tolerance and Addiction
These terms do not mean the same thing.
Physical dependence means the body has adapted to oxycodone. Withdrawal symptoms may occur if the medicine is stopped suddenly.
Tolerance means the same dose may have less effect after repeated use.
Addiction, also called opioid use disorder, involves a loss of control over opioid use despite harmful results.
A person can develop physical dependence while taking oxycodone exactly as prescribed. This does not automatically mean that person has an addiction.
Do not suddenly stop oxycodone after regular use. A clinician may need to reduce the dose slowly through a personal tapering plan.
Could an RP 10 Pill Be Counterfeit
Yes. Counterfeit pills may copy the shape, color, and imprint of prescription oxycodone. Some fake pills contain fentanyl, methamphetamine, the wrong amount of medicine, or no oxycodone at all.
You cannot confirm a counterfeit pill by looking at it. Warning signs may include:
- The pill came from a friend, dealer, social media seller, or unlicensed website
- The packaging looks different from your usual prescription
- The pill has an unusual color, texture, smell, or imprint
- The effects feel different from your prescribed medicine
- There is no pharmacy label with the patient’s name and instructions
The safest medication is one prescribed to you and supplied by a licensed pharmacy. Do not take an unknown pill to test its effects.
RP 10 Overdose Signs
If oxycodone is kept in your home, ask a prescriber or pharmacist how to obtain naloxone and make sure other household members know where it is stored.
An oxycodone overdose can stop a person from breathing. Warning signs include:
- Very slow, shallow, or stopped breathing
- Choking, gurgling, or unusual snoring sounds
- Extreme sleepiness or inability to wake up
- Limp muscles
- Cold or clammy skin
- Pinpoint pupils
- Slow heartbeat
- Blue, gray, or pale lips and fingertips
- Loss of consciousness
What to Do
- Give naloxone if it is available, then call 911.
- If the person does not wake up or start breathing normally within two to three minutes, give another dose using a new naloxone device.
- Place the person on their side, stay with them, and follow the naloxone product instructions until emergency help arrives.
- Do not assume the danger is over when the person wakes up. Naloxone may wear off before oxycodone does.
Naloxone can temporarily reverse an opioid overdose, but emergency care is still required.
What If Someone Accidentally Took an RP 10 Pill
If someone took an unknown RP 10 pill, call Poison Control at 1-800-222-1222, even if no symptoms have appeared. Some effects may be delayed. Have the imprint, estimated number of tablets, and approximate time of ingestion ready. Do not make the person vomit.
Call 911 immediately if the person has collapsed, cannot be awakened, has a seizure, or is struggling to breathe.
Safe Storage and Disposal
Store RP 10 tablets at room temperature in a tight, light-resistant container. Protect them from moisture and keep them securely out of sight and reach of children, visitors, and pets.
Keep track of how many tablets remain. Missing pills may be a sign of accidental access, theft, or misuse.
Use an authorized medication take-back program when one is available. If you cannot quickly reach a take-back site, the current oxycodone label instructs patients to flush unused tablets down the toilet. Do not give leftover tablets to another person.
Final Safety Message
Real-world pill identification is rarely as simple as matching a photo. Pharmacy practice follows one reliable rule: identify a pill from its complete imprint and trusted source, never its color or a partial marking. A white, round pill marked R/P on one side and 10 on the other is commonly identified as immediate-release oxycodone hydrochloride 10 mg, while RP 10 325 and similar pills contain different ingredients. If the pill is loose, damaged, obtained outside a licensed pharmacy, or does not match its labeled container, do not take it. Ask a pharmacist to confirm its identity, and call 911 for slow breathing, extreme sleepiness, or inability to wake.
This article provides general information and is not a substitute for medical advice, diagnosis, or treatment. Take oxycodone only as prescribed. Call 911 for signs of an opioid overdose.
References
1. Drugs.com R P 10 Pill Identification
2. Drugs.com RP 10 325 Pill Identification
3. Drugs.com Ramipril RP 10 Pill Identification
4. Drugs.com RP 10 mg Lisdexamfetamine Pill Identification
5. Drugs.com RP 10 300 Hydrocodone and Acetaminophen Pill Identification